Mitochondria control of physiology and disease: beyond ATP

Mitochondria control of physiology and disease: beyond ATP

Mitochondria control of physiology and disease: beyond ATP

Air date: Wednesday, March 7, 2018, 3:00:00 PM

Category: WALS – Wednesday Afternoon Lectures

Runtime: 00:57:53

Description: NIH Director’s Wednesday Afternoon Lecture Series

Historically, mitochondria have been primarily viewed as biosynthetic and bioenergetic organelles that generate metabolites for the production of macromolecules and adenosine triphosphate (ATP), respectively. The work of the Chandel laboratory has elucidated that mitochondria have a third distinct role whereby they release reactive oxygen species (ROS) and metabolites to regulate transcription factors and epigenetics. For his lecture, Dr. Chandel will present his lab’s ongoing efforts to understand how mitochondria, in addition to producing ATP, regulate cancer and immunity.

For more information go to https://oir.nih.gov/wals/2017-2018

Author: Navdeep S. Chandel, Ph.D., David W. Cugell Professor of Medicine, Northwestern University

Permanent link: https://videocast.nih.gov/launch.asp?23744

Exercise intensity perceptions in active people – Video abstract [ID 63496]

Exercise intensity perceptions in active people – Video abstract [ID 63496]

Video abstract of an original research paper “People who perceive themselves as active cannot identify the intensity recommended by the international physical activity guidelines” published in the Open Access Journal of Sports Medicine by Prokop, Hrubeniuk, Sénéchal, et al.

Background: Many national and international organizations recommend that adults achieve at least 150 minutes of aerobic physical activity (PA) weekly, at a minimum moderate intensity to optimize health benefits. It is unknown if people who consider themselves as active have the ability to identify what is considered moderate intensity.

Methods: Fifty-one participants who reported achieving a minimum 150 minutes per week at a minimum of moderate intensity PA were recruited through a local fitness facility. All participants underwent a single assessment involving questionnaires, clinical measures, and a treadmill test to measure the ability to perceive moderate intensity. Following the visit, participants’ PA level was evaluated by heart rate monitor, while exercising, for 7 consecutive days.

Results: Eighty percent of participants overestimated moderate intensity on the treadmill test; they were at vigorous intensity compared to what is considered moderate. Only 11.8% of participants accurately identified moderate intensity; all of them were women (P=0.03), had a high level of education (P=0.04), and knew that moderate intensity was the minimum intensity recommended by health organizations (P,0.01). Only 69.2% of participants reached the aerobic component of the International Physical Activity Guidelines with no significant advantage for those correctly identifying moderate intensity.

Conclusion: Most people who perceive themselves as active are exercising at vigorous intensity while believing they are at moderate intensity. In addition, in this active sample, one-third of the participants were not reaching the aerobic component of the International Physical Activity Guidelines.

Read the original research paper here: http://www.dovepress.com/people-who-perceive-themselves-as-active-cannot-identify-the-intensity-peer-reviewed-article-OAJSM

Exercise therapy for mental illness

Exercise therapy for mental illness

Research conducted by UNSW and Black Dog Institute has found a direct link between physical exercise and improvement in symptoms of depression, anxiety and Post Traumatic Stress Disorder. Dr Simon Rosenbaum explains.
More info on Black Dog Institute:
https://www.blackdoginstitute.org.au/

For more factual videos like this subscribe. http://www.youtube.com/user/unsw?sub_confirmation=1 We’re the official channel of UNSW Sydney, a brilliantly located university between the coast and the city.

Guided Relaxation Exercise For Anxiety – Mental Health Resources

Guided Relaxation Exercise For Anxiety – Mental Health Resources

Struggling to relax your body and mind? Give this guided relaxation audio exercise a try to help ease your anxiety.

Take 10 minutes out of your day to give yourself a break. #guidedrelaxation #relaxation #anxietyrelaxation

This guided relaxation exercise is split in to 2 parts, firstly we look at slowing and regulating your breathing and then moving on to a progressive muscle relaxation exercise.

Relaxation should be an important part of your daily routine, slowing down your racing thoughts and giving your body time to recover from any stress.

You can find more free resources for anxiety and other mental health issues on our website at http://www.anxietyunited.com