Mitochondria control of physiology and disease: beyond ATP
Air date: Wednesday, March 7, 2018, 3:00:00 PM
Category: WALS – Wednesday Afternoon Lectures
Description: NIH Director’s Wednesday Afternoon Lecture Series
Historically, mitochondria have been primarily viewed as biosynthetic and bioenergetic organelles that generate metabolites for the production of macromolecules and adenosine triphosphate (ATP), respectively. The work of the Chandel laboratory has elucidated that mitochondria have a third distinct role whereby they release reactive oxygen species (ROS) and metabolites to regulate transcription factors and epigenetics. For his lecture, Dr. Chandel will present his lab’s ongoing efforts to understand how mitochondria, in addition to producing ATP, regulate cancer and immunity.
For more information go to https://oir.nih.gov/wals/2017-2018
Author: Navdeep S. Chandel, Ph.D., David W. Cugell Professor of Medicine, Northwestern University
We all know exercise is good for us, but what actually happens inside your body when you get active? Watch to find out, and learn more about the benefits of exercise for your heart. For more information about getting active, visit http://www.bhf.org.uk/activity
Video abstract of an original research paper “People who perceive themselves as active cannot identify the intensity recommended by the international physical activity guidelines” published in the Open Access Journal of Sports Medicine by Prokop, Hrubeniuk, Sénéchal, et al.
Background: Many national and international organizations recommend that adults achieve at least 150 minutes of aerobic physical activity (PA) weekly, at a minimum moderate intensity to optimize health benefits. It is unknown if people who consider themselves as active have the ability to identify what is considered moderate intensity.
Methods: Fifty-one participants who reported achieving a minimum 150 minutes per week at a minimum of moderate intensity PA were recruited through a local fitness facility. All participants underwent a single assessment involving questionnaires, clinical measures, and a treadmill test to measure the ability to perceive moderate intensity. Following the visit, participants’ PA level was evaluated by heart rate monitor, while exercising, for 7 consecutive days.
Results: Eighty percent of participants overestimated moderate intensity on the treadmill test; they were at vigorous intensity compared to what is considered moderate. Only 11.8% of participants accurately identified moderate intensity; all of them were women (P=0.03), had a high level of education (P=0.04), and knew that moderate intensity was the minimum intensity recommended by health organizations (P,0.01). Only 69.2% of participants reached the aerobic component of the International Physical Activity Guidelines with no significant advantage for those correctly identifying moderate intensity.
Conclusion: Most people who perceive themselves as active are exercising at vigorous intensity while believing they are at moderate intensity. In addition, in this active sample, one-third of the participants were not reaching the aerobic component of the International Physical Activity Guidelines.
Read the original research paper here: http://www.dovepress.com/people-who-perceive-themselves-as-active-cannot-identify-the-intensity-peer-reviewed-article-OAJSM
Chris Simone, physical therapist at St. John Hospital and Shannon Tokarski, a nutritionist St. John Providence Weight Loss, were featured in a segment on WXYZ-TV 7 called “Healthy You.” The pair discussed the importance of healthy eating and exercise.
Caring for your spine is something that can start at the gym. We teamed up with trainer Kai Karlstrom of Equinox to get some great tips on how to strengthen our spines, and to find out how to protect them as we get moving.
Research conducted by UNSW and Black Dog Institute has found a direct link between physical exercise and improvement in symptoms of depression, anxiety and Post Traumatic Stress Disorder. Dr Simon Rosenbaum explains.
More info on Black Dog Institute:
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